jio wrote:As I said before you can believe what you like. I dont doubt prep's efficiency in preventing infections. I doubt the effects on the big picture meaning overall infection rates (given the change in attitutes towards safer sex) other stds and effects on long-term health of individuals. If there was no alternative Id say very well but since there is I dont see any purpose in arguing this. It is simple.
Long-term effects are a moot point to begin with, as anyone suffering from a short-term effect, ie anyone with a declining kidney function while on PrEP below healthy levels, is taken off PrEP completely. If they continue taking it despite the medical advice against their taking it, then they're abusing it.
There cannot be long-term effects if only people with no short-term issues with the kidney could continue taking it.
Some other published research:https://www.thelancet.com/journals/lanh ... 52-3018(18
)30215-7/fulltextHIV diagnoses in MSM in New South Wales declined from 295 in the 12 months before PrEP roll-out to 221 in the 12 months after (relative risk reduction [RRR] 25·1%, 95% CI 10·5–37·4). There was a decline both in recent HIV infections (from 149 to 102, RRR 31·5%, 95% CI 11·3 to 47·3) and in other HIV diagnoses (from 146 to 119, RRR 18·5%, 95% CI −4·5 to 36·6)...PrEP implementation was associated with a rapid decline in HIV diagnoses in the state of New South Wales...http://www.aidsmap.com/page/3313879/In San Francisco, where the city's large gay community [b]adopted PrEP early on, new infections fell to their lowest-ever level in 2016
...a dramatic recent decline in new infections among gay men attending sexual health clinics in London
– representing a very high-risk population – and a large decrease among men who have sex with men in Sydney
have also been attributed to a combination of approaches including stepped up testing, treatment and PrEP
...The overall HIV diagnosis rate decreased significantly, from 15.7 per 100,000 persons in 2012 to 14.5 per 100,000 persons in 2016
, an estimated annual decline of -1.6% per year...[/b]